China (Mainland)
Tacrolimus CAS NO.104987-11-3
- Min.Order: 1 Metric Ton
- Payment Terms: L/C,D/A,D/P,T/T,
- Product Details
Keywords
- Tacrolimus
- Tacrolimus Monohydrate
- 109581-93-3
Quick Details
- ProName: Tacrolimus
- CasNo: 104987-11-3
- Molecular Formula: C44H69NO12
- Appearance: white crystalline powder
- Application: Pharmaceutical intermediates
- DeliveryTime: With three or five working days
- PackAge: 25kg/fiber drum, sealed package
- Port: China main port
- ProductionCapacity: 10 Metric Ton/Month
- Purity: 99.3%
- Storage: Seald package, keep away from light
- Transportation: Sealed package, keep away from light
- LimitNum: 1 Metric Ton
- Valid Period: 2019-12-18
Superiority
1. Advanced facility and Equipment
2. Competent technical team
3 .Strong R & D support
4,high quality products with high stability
5, Competitive price
5.Customer tailored service
Details
Introduction:
Tacrolimus is a macrolide immunosuppressant produced by Streptomyces tsukubaensis. Tacrolimus is used to prevent rejection of organ transplants. Tacrolimus is 10 to 100 times superior to cyclosporin in improving graft survival and preventing acute rejection after transplantation, but decreasing the toxin side effects.
Certificate of Analysis for Tacrolimus :
|
Tests |
Specifications |
Results |
|
Description |
A white or off-white crystalline powder |
Conform |
|
Identification |
1. IR (USP <197K>) |
Conform |
|
2. HPLC retention times |
Conform |
|
|
Water (USP <921> Method I) |
1.6 ~ 3.0% |
2.1% |
|
Residue on ignition (USP <281>) |
£ 0.2% |
0.08% |
|
Heavy metals (USP <231> II) |
£ 20 ppm |
< 20 ppm |
|
Related substances (In-house HPLC method) |
Ascomycin £ 0.8% |
0.064% |
|
Dihydrotacrolimus £ 0.6% |
0.089% |
|
|
Total impurities £ 1.5% |
0.15% |
|
|
Residual solvents (In-house method) |
Acetone £ 2000 ppm |
Not detected |
|
Ethanol £ 2000 ppm |
Not detected |
|
|
Assay (on anhydrous basis) |
98.0% ~ 102.0% |
100.0% |
|
Conclusion: Complied with In-House standard |
||
